Akmal Yarashev

Abstract: Acute ischemic stroke affects millions of people every year. Recent research data indicate the involvement of the glymphatic system in the process. The balance of pro- and anti-inflammatory interleukins is one of the pathogenetic mechanisms of the development of neuroinflammation that determines the course and outcome of ischemic stroke.The development of neuroinflammation during the acute phase of ischemic stroke leads to secondary damage and subsequently to various complications.The discoveries of meningeal lymphatic vessels in the human brain have changed our understanding of the mechanisms of neuroinflammation in ischemic stroke, suggesting that glymphatic dysfunction underlies immune dysfunction and central nervous system drainage.In this presentation, I will review methods of influencing the pathogenetic link of neuroinflammation by administering a drug lymphotropically.

Speaker: Yarashev Akmal Rustamovich – head of the neuroreanimation department of the Bukhara branch of the Republican Scientific Center for Emergency Medical Care, assistant of the Department of Anesthesiology and Reanimatology of the Bukhara State Medical Institute.He completed clinical residency in anesthesiology and resuscitation at the Bukhara Medical Institute in 2002-2004, and postgraduate studies at the Tashkent Institute for Advanced Medical Studies and Postgraduate Education in 2007-2010.In 2010, he defended his Ph.D. thesis on the topic “Monitoring of cerebral perfusion pressure in intensive care for hemorrhagic stroke” at the Academic Council of the Tashkent Medical Academy.During his medical career, he completed an internship in stroke centers in Germany, Turkey, India and Japan.

Scientific activity of Yarashev A.R. focused on studying the problem of neuroinflammation and developing new methods of intensive therapy for cerebrovascular diseases. He is the author of more than 60 publications - theses, articles and methodological recommendations.