Olim Eshonov

Abstract: Secondary damage after traumatic brain injury is a serious problem in neurocritical care, which leads to increased neuroinflammation and cerebral edema. It is known that secondary brain lesions play a significant role in the pathogenesis of severe closed traumatic brain injury, leading to edema, increased intracranial pressure, dislocation of vital centers and unfavorable outcome.Despite a number of factors influencing the high mortality associated with traumatic brain injury, the development of cerebral edema is the most significant predictor of unfavorable outcome.Various pharmacological treatment options have not demonstrated benefit in traumatic brain injury.In this presentation, I will review clinical developments to target neuroinflammation and cerebral edema in traumatic brain injury in the context of recent progress made in the field of the glymphatic system of the brain.

Speaker: Olim Sh. Eshonov – Associate Professor of the Department of Anesthesiology and Reanimatology, Bukhara State Medical Institute.He underwent specialization and advanced training at the Institute of Emergency and Emergency Care named after. Sklifosovsky in Moscow 1984 1986, 1991 on the basis of the Moscow Medical Academy in the “Clinical Lymphology” cycle.In 1991, he defended his PhD thesis at the Moscow Medical Academy on the topic “Endolymphatic antibiotic therapy for acute septic brucellosis.”His research focuses on developing new treatments for traumatic brain injury, stroke and other cerebrovascular diseases.

Dr. Eshonov is the author of more than 150 publications and textbooks “Anesthesiology and Resuscitation” and “Emergency Conditions”, the manual “Anesthesiology, Resuscitation and Intensive Care”, received three patents for new methods of treating and diagnosing diseases.