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Complex system and future technologies in neuroscience – CSFTN’26
09-10 June 2026 Moscow, Russia

Peng Xiao

PET instrument for freely behaving animals

Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan National Laboratory for Optoelectronics Wuhan 430074, China

PET instrument for freely behaving animals

Abstract: Brain science is currently a highly challenging research hotspot, and in vivo brain function observation in living animals is critical to its advancement. As a non-invasive functional imaging modality, positron emission tomography (PET) offers unique advantages in such applications. However, conventional animal PET imaging requires the subject to be anesthetized or restrained, resulting in a non-awake or non-free-moving state; the observed outcomes therefore do not reflect the normal state of brain function. Meanwhile, brain function is dynamically changing, and existing animal PET systems cannot simultaneously achieve satisfactory temporal resolution and image quality, making it difficult to meet the demands of dynamic brain function observation. We have developed a “Bi-Dynamic” PET instrument capable of dynamic imaging in awake and freely moving animals, enabling high-temporal-resolution and high-spatial-resolution dynamic imaging of the rat brain.

Speaker: Dr. Peng Xiao is a professor at Huazhong University of science and technology (HUST). He obtained his PhD degree from the National University of Singapore (NUS). After working two years in the R&D Department STMicroelectronics Asia, Dr. Xiao joined HUST to pursue his academic career in 2006. He has been actively working in innovative reconstruction algorithms and instrumentation development for Positron Emission Tomography, as well as its applications in biology and medicine. He has owned more than 70 papers in journals including Physics in Medicine and Biology, IEEE Transactions on Radiation and Plasma Medical Sciences, and Computer Methods and Programs in Biomedicine. He is also a co-founder of RaySolution Medical Imaging Technology Co., Ltd., which commercializes the “all-digital PET” technology.